Research Articles


Plasma-derived Exosomes Reverse Epithelial-to-Mesenchymal

Transition after Photodynamic Therapy of Patients with Head

and Neck Cancer.

Theodoraki MN, Yerneni S, Brunner C, Theodorakis J, Hoffmann TK, Whiteside TL.

2018 Apri 29. 

Cancer Research

Helicase-driven activation of NFκB-COX2 mediates the immunosuppressive component of dsRNA-driven inflammation in the human tumor microenvironment.

Theodoraki MN, Yerneni S, Sarkar SN, Orr B, Muthuswamy R, Voyten J, Modugno F, Jiang W, Grimm M, Basse PH, Bartlett DL, Edwards R, Kalinski P.

Cancer Res. 2018 May 31. pii: canres.3985.2017. doi: 10.1158/0008-5472.CAN-17-3985 

Clinical and Experimental Immunology

Separation of plasma-derived exosomes into CD3(+) and CD3(-) fractions allows for association of immune cell and tumor cell markers with disease activity in HNSCC patients. 

Theodoraki MN, Hoffmann TK, Whiteside TL.  

2018 Feb 12. doi: 10.1111/cei.13113

Clinical Cancer Research

Clinical significance of PD-L1+ exosomes in plasma of Head and Neck Cancer patients. 

Theodoraki MN, Yerneni S, Hoffmann TK, Gooding WE, Whiteside 2017 Dec 12.  doi: 10.1158/1078-0432

Infectious Agents and Cancer

Synchronous bilateral tonsil carcinoma: case presentation and review of the literature. 

Theodoraki MN, Veit JA, Hoffmann TK 

 2017 Jun 26. doi: 10.1186/s13027-017-0146-5 

Photodiagnosis and Photodynamic Therapy


Influence of photodynamic therapy on peripheral immune cell populations and cytokine concentrations in head and neck cancer. 

Theodoraki MN, Lorenz K, Lotfi R, Fürst D, Tsamadou C, Jaekle S, Mytilineos J, Brunner C, Theodorakis J, Hoffmann TK, Laban S, Schuler PJ. 

2017 May 31. doi: 10.1016/j.pdpdt.2017.05.015

Clinical Cancer Research

Suppression of lymphocyte functions by plasma exosomes correlates with disease activity in patients with head and neck cancer. 

Ludwig S, Floros T, Theodoraki MN, Hong CS, Jackson EK, Lang S, Whiteside TL. Clin Cancer Res. 

2017 Apr 11. doi: 10.1158/1078-0432.CCR-16-2819.


MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrence implications for immunotherapy.

Laban S, Giebel G, Klümper N, Schröck A, Doescher J, Spagnoli G, Thierauf J, Theodoraki MN, Remark R, Gnjatic S, Krupar R, Sikora AG, Litjens G, Grabe N, Kristiansen G, Bootz F, Schuler PJ, Brunner C, Brägelmann J, Hoffmann TK, Perner S.

Oncotarget, 2017 Jan;

Annals of ORL

Surgery of anterior skull base lesions in children. 

Hoffmann TK., Scheithauer MO, Sommer F, Lindemann J, Haberl EJ, Friebe-Hoffmann U, Theodoraki MN

2017 Mar; 126(3): 245-253

Anticancer Research


Influence of Photodynamic Therapy on the Expression of Cancer/Testis Antigens in Squamous Cell Carcinoma of the Head and Neck.

Theodoraki MN, Lorenz KJ, Schneider J, Thierauf JC, Spagnoli G, Schuler PJ, Hoffmann TK, Laban S. 

2016 Aug;36(8):3973-82

 European Archives of ORL 

Specific stressors in endonasal skull base surgery with and without navigation

Stelter K, Theodoraki MN, Becker S, Tsekmistrenko V, Olzowy B, Ledderose G.

2014 March 28. doi:

 European Archives of ORL 

Mental distress and effort to engage an image-guided navigation system in the surgical training of endoscopic sinus surgery: a prospective, randomised clinical trial.

Theodoraki M-N, Ledderose Georg, Becker Sven, Leunig Andreas, Arpe Sarah, Luz Maria, Stelter Klaus; 

2014 July 14. doi: 

 Annals of Otolaryngology Rhinolology Laryngology

Evaluation of Customized Prosthesis for Irregularly Formed Tracheostoma After Laryngectomy.

Doescher J, Scheckenbach K, Angerstein W, Veit JA, Laban S, Thierauf J, Theodoraki MN, Greve J, Schuler PJ, Hoffmann TK

2015 August 25 


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